Manuel's SpaceOAR™ Hydrogel Story

In 2018 during an annual physical, Manuel’s primary care physician discovered he had a high prostate-specific antigen (PSA) level. After undergoing a prostate biopsy, Manuel was diagnosed with stage 4 prostate cancer.

Manuel and his medical team opted for radiation therapy to treat his prostate cancer. They also chose SpaceOAR Hydrogel, a pre-treatment option, that has been shown to help minimize the side effects that may occur as a result of radiation therapy.1–3

Watch Manuel’s Story

Radiation therapy uses high-powered energy to target cancer cells and may be delivered in multiple ways including external beam radiotherapy and brachytherapy (internal radiation).4 SpaceOAR Hydrogel is designed to be used with radiation therapy. Learn more about radiation therapy for prostate cancer.”

“Don’t feel depressed, there is always a way and think positive.” — Manuel

Results from case studies are not necessarily predictive of results in other cases. Results in other cases may vary. Boston Scientific strongly recommends that you consult with your physician on all matters pertaining to your health or to address any questions.

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*Please note, there may be other doctors in your area who treat prostate cancer not listed here.

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  1. Mariados N, Sylvester J, Shah D, et al. Hydrogel spacer prospective multicenter randomized controlled pivotal trial: Dosimetric and clinical effects of perirectal spacer application in men undergoing prostate image guided intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):971–7.
  2. Hamstra DA, Mariados N, Sylvester J, et al. Continued benefit to rectal separation for prostate radiation therapy: Final results of a phase III trial. Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):976–85.
  3. Karsh LI, Gross ET, Pieczonka CM, et al. Absorbable hydrogel spacer use in prostate radiotherapy: A comprehensive review of phase 3 clinical trial published data. Urology. 2018 May;115:39–44.
  4. Radiation Therapy for Prostate Cancer. American Cancer Society. https://www.cancer.org/cancer/prostate-cancer/treating/radiation-therapy.html. Accessed March 4, 2022.

Caution: U.S. Federal law restricts this device to sale by or on the order of a physician

SpaceOAR Hydrogel is intended to temporarily move the rectal wall away from the prostate during the course of radiotherapy treatment for prostate cancer, and in creating this space it is the intent of SpaceOAR Hydrogel to reduce the radiation dose affecting the rectum.

SpaceOAR Hydrogel contains polyethylene glycol (PEG). As with any medical treatment, there are some risks involved with the use of SpaceOAR Hydrogel. Potential complications associated with SpaceOAR Hydrogel include, but are not limited to: pain associated with injection, pain or discomfort from the hydrogel, site inflammation, infection (including abscess), inability to urinate, urgent need to urinate, constipation, rectal muscle spasm, damage to lining of rectum, ulcers, fistula (a hole between rectum and bladder, urethra, or skin below the scrotum), perforation (hole in prostate, bladder, urethra, rectum), necrosis (dead tissue), allergic reaction (local reaction or more severe reaction, such as anaphylaxis), embolism (blood vessel blockage is possible and may happen outside of the pelvis, potentially impacting vital organs or legs), fainting, and bleeding. Please talk to your doctor about the risks and benefits related to using SpaceOAR Hydrogel. If one or more of these complications occur, you may need medical treatment or surgery. URO-1288805-AA

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